Conserved Site

ADP-glucose pyrophosphorylase, conserved site (IPR005836)

Short name: ADP_Glu_pyroP_CS

Description

ADP-glucose pyrophosphorylase (glucose-1-phosphate adenylyltransferase) [PMID: 1657244] (EC:2.7.7.27) catalyzes a very important step in the biosynthesis of alpha 1,4-glucans (glycogen or starch) in bacteria and plants: synthesis of the activated glucosyl donor, ADP-glucose, from glucose-1-phosphate and ATP.

ADP-glucose pyrophosphorylase is a tetrameric allosterically regulated enzyme. It is a homotetramer in bacteria while in plant chloroplasts and amyloplasts, it is a heterotetramer of two different, yet evolutionary related, subunits.

There are a number of conserved regions in the sequence of bacterial and plant ADP-glucose pyrophosphorylase subunits.

GO terms

Biological Process

GO:0005978 glycogen biosynthetic process

Molecular Function

GO:0008878 glucose-1-phosphate adenylyltransferase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns
PROSITE patterns
PROSITE patterns