Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA (IPR005815)

Short name: BioA

Overlapping homologous superfamilies

Family relationships


BioA is an adenosylmethionine-8-amino-7-oxononanoate aminotransferase that functions in biotin synthesis. It utilises S-adenosyl-L-methionine (SAM) to transaminate the biotin precurson 7-keto-8-aminopelargonic acid and form the next intermediate in the pathway, 7, 8-diaminopelargonic acid [PMID: 1092681]. It is currently the only aminotransferase that is known to use SAM as an amino donor. donor. The Bacillus subtilis enzyme, which is included in this entry, uses lysine rather than SAM as the amino donor [PMID: 15880481].

GO terms

Biological Process

GO:0009102 biotin biosynthetic process

Molecular Function

GO:0004015 adenosylmethionine-8-amino-7-oxononanoate transaminase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.