Family

Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein (IPR005770)

Short name: PhnD

Overlapping homologous superfamilies

None.

Family relationships

Description

This family includes the periplasmic binding protein component of ABC transporters for phosphonates [PMID: 16751609] as well as other related binding components for closely related substances such as phosphate [PMID: 17074913] and phosphite [PMID: 15317793]. A number of members of this family are found in genomic contexts with components of selenium metabolic processes, suggestive of a role in selenate or other selenium-compound transport.

Phosphonates are a varied class of phosphorus-containing organic compound in which a direct C-P bond is found, rather than a C-O-P linkage of the phosphorus through an oxygen atom. They may be toxic but also may be used as sources of phosphorus and energy by various bacteria. Phosphonate utilization systems typically are encoded in 14 or more genes, including a three gene ABC transporter. This family includes the periplasmic binding protein component of ABC transporters for phosphonates [PMID: 16751609] as well as other, related binding components for closely related substances such as phosphate [PMID: 15317793] and phosphite. A subset of this entry in which nearly all members exhibit genomic context with elements of phosphonate metabolism, particularly the C-P lyase system (GenProp0232, [PMID: 8335257]) is shown in (IPR017797). Nevertheless, there are members of this subfamily which show up sporadically on a phylogenetic tree that also show phosphonate context and are most likely competent to transport phosphonates.

GO terms

Biological Process

GO:0055085 transmembrane transport

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0043190 ATP-binding cassette (ABC) transporter complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs