Mitochondrial import receptor subunit Tom22 (IPR005683)

Short name: Tom22

Overlapping homologous superfamilies


Family relationships


The mitochondrial protein translocase family, which is responsible for movement of nuclear encoded pre-proteins into mitochondria, is very complex with at least 19 components. These proteins include several chaperone proteins, four proteins of the outer membrane translocase (Tom) import receptor, five proteins of the Tom channel complex, five proteins of the inner membrane translocase (Tim) and three "motor" proteins. This family represents the Tom22 proteins [PMID: 11866524]. The N-terminal region of Tom22 has been shown to have chaperone-like activity, and the C-terminal region faces the intermembrane face [PMID: 14699115].

GO terms

Biological Process

GO:0006886 intracellular protein transport

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005741 mitochondrial outer membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.