Chromosome partition protein MukF (IPR005582)

Short name: Chromosome_partition_MukF

Overlapping homologous superfamilies

Family relationships



This family contains MukF, which are proteins involved in chromosome condensation, segregation and cell cycle progression. MukE along with MukF interact with MukB in vivo forming a complex, which is required for chromosome condensation and segregation in Escherichia coli [PMID: 10545099]. The Muk complex appears to be similar to the SMC-ScpA-ScpB complex in other prokaryotes where MukB is the homologue of SMC [PMID: 12065423]. ScpA and ScpB have little sequence similarity to MukE or MukF, though they are predicted to be structurally similar, being predominantly alpha-helical with coiled coil regions. The structure of MuKF has been revealed [PMID: 15902272].

GO terms

Biological Process

GO:0006260 DNA replication
GO:0007059 chromosome segregation

Molecular Function

GO:0005509 calcium ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.