Family

CD36/scavenger receptor class B member 1 (IPR005428)

Short name: CD36/SCARB1/SNMP1

Family relationships

  • CD36 family (IPR002159)
    • CD36/scavenger receptor class B member 1 (IPR005428)

Description

This entry includes platelet glycoprotein 4 (CD36) and scavenger receptor class B member 1 (SCARB1, also known as CD36 antigen-like 1) from humans, and sensory neuron membrane protein 1 (SNMP1) from flies.

CD36 is a a scavenger receptor important for lipoprotein binding and uptake of cholesterol and lipids in vertebrates [PMID: 10865832].

SCARB1 plays an important role in the uptake of HDL cholesteryl ester [PMID: 9291126]. It acts as a receptor for hepatitis C virus in hepatocytes [PMID: 21489334].

SNMP1 is a homologue of CD36. SNMP1 has a role in detection and signal transduction of the fatty-acid-derived male pheromone 11-cis vaccenyl acetate (cVA) [PMID: 18653762].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PRINTS