Family

ER membrane protein complex subunit 8/9 (IPR005366)

Short name: EMC8/9

Family relationships

None.

Description

Saccharomyces cerevisiae ER membrane protein complex (EMC) comprises six subunits [PMID: 19325107]. Four and three additional subunits have been identified in mammals and Drosophila, respectively [PMID: 22119785]. EMC is required for protein folding in the endoplasmic reticulum (ER). It also facilitates lipid transfer from ER to mitochondria [PMID: 25313861].

This family includes mammalian subunits EMC8 and EMC9, and Drosophila EMC8/9 homologue [PMID: 25715730]. EMC8 is also known as neighbour of COX4 (NOC4) [PMID: 10337626].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD
PANTHER
Pfam