Family

Mitochondrial pyruvate carrier (IPR005336)

Short name: MPC

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This entry represents the mitochondrial pyruvate carrier proteins, including Mpc 1/2 and their homologues. They mediate the uptake of pyruvate into mitochondria [PMID: 22628558]. In humans, Mpc1 and Mpc2 associate to form an ~150-kilodalton complex in the inner mitochondrial membrane [PMID: 22628558].

GO terms

Biological Process

GO:0006850 mitochondrial pyruvate transmembrane transport

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005743 mitochondrial inner membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam