Family

MOB kinase activator family (IPR005301)

Short name: MOB_kinase_act_fam

Family relationships

None.

Description

The MOB kinase activator family includes MOB1, an essential Saccharomyces cerevisiae protein, identified from a two-hybrid screen, that binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Conditional alleles of MOB1 cause a late nuclear division arrest at restrictive temperature [PMID: 9436989]. This family also includes the MOB-like protein phocein, an intracellular protein that interacts with striatin and may play a role in membrane trafficking [PMID: 11872741].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SMART
Pfam
PANTHER