Lytic transglycosylase MltA, domain B (IPR005300)

Short name: MltA_B

Overlapping homologous superfamilies

Domain relationships


Escherichia coli MltA is a membrane-bound lytic transglycosylase comprised of two domains separated by a large groove, where the peptidoglycan strand binds. Domain A is made up of an N-terminal and a C-terminal portion, which correspond to the 3D domain, named for 3 conserved aspartate residues. Domain B is inserted within the linear sequence of domain A [PMID: 16139297, PMID: 16618494, PMID: 17502382].

MltA is a membrane-bound, murein degrading transglycosylase enzyme that plays an important role in the controlled growth of the stress-bearing sacculus of E. coli [PMID: 10037771, PMID: 9287002].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.