Family

Pigment precursor permease/ProteinATP-binding cassette sub-family G (IPR005284)

Short name: Pigment_permease/Abcg

Family relationships

  • Pigment precursor permease/ProteinATP-binding cassette sub-family G (IPR005284)

Description

This family includes pigment precursor permeases (protein white, brown and scarlet) from flies and ATP-binding cassette sub-family G member 1 (ABCG1) from mammals.

The fly pigment precursor permeases are membrane-spanning proteins necessary for the transport of pigment precursor into pigment cells responsible for eye colour. White protein dimerises with brown protein for the transport of guanine and with scarlet protein for the transport of tryptophan [PMID: 3149712].

ABCG1 is an ABC half transporter that facilitates efflux excess cholesterol from macrophages [PMID: 14668945, PMID: 21039336].

GO terms

Biological Process

GO:0055085 transmembrane transport

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs