Peroxysomal long chain fatty acyl transporter (IPR005283)
Short name: FA_transporter
Overlapping homologous superfamilies
Eukaryotic ABC transporters are found either as complete transporters or as half transporters, which dimerise to form an active transporter. Four half ABC transporter proteins have been identified in the human peroxisome membrane: the 70 kDa peroxisomal membrane protein (PMP70), the adrenoleukodystrophy protein (ALDP), the PMP70-related protein (P70R) and the ALDP-related protein (ALDR) [PMID: 11248239]. This entry includes PMP70 [PMID: 1301993, PMID: 11883951] (renamed as ATP-binding cassette sub-family D member 3, ABCD3) and ALDP [PMID: 8441467, PMID: 18757502] (ATP-binding cassette sub-family D member 1, ABCD1) from human, and yeast peroxisomal long-chain fatty acid import proteins PAT1 (PXA2) and PAT2 (PXA1) [PMID: 8670886].
The members of this family are involved in the import of activated long-chain fatty acids from the cytosol to the peroxisomal matrix.
GO:0015910 peroxisomal long-chain fatty acid import
- TIGR00954 (3a01203)