Anthranilate synthase component I, TrpE-like, bacterial (IPR005257)

Short name: Anth_synth_I_TrpE

Overlapping homologous superfamilies

Family relationships


This family represents anthranilate/para-aminobenzoate synthase component I from proteobacteria and actinobacteria.

This enzyme resembles some other chorismate-binding enzymes, including para-aminobenzoate synthase (pabB) and isochorismate synthase. There is a fairly deep split between two sets, seen in the pattern of gaps as well as in amino acid sequence differences. This group includes proteobacteria such as Escherichia coli and Helicobacter pylori (Campylobacter pylori) but also the Gram-positive organism Corynebacterium glutamicum. The second group (IPR005256) includes eukaryotes, archaea, and most other bacterial lineages; sequences from the second group may resemble pabB more closely than other trpE from this group.

GO terms

Biological Process

GO:0009058 biosynthetic process

Molecular Function

GO:0004049 anthranilate synthase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.