Alpha glucuronidase, N-terminal (IPR005154)

Short name: Glyco_hydro_67_aGlcAse_N

Overlapping homologous superfamilies

Domain relationships



O-Glycosyl hydrolases (EC:3.2.1.) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [PMID: 7624375, PMID: 8535779]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site.

This represents a family of alpha-glucuronidases (GH67). Deletion mutants have indicated that the central region is responsible for the catalytic activity. Within this central domain, the invariant Glu and Asp (residues 391 and 364 respectively from Bacillus stearothermophilus (Geobacillus stearothermophilus)) are thought to from the the catalytic centre [PMID: 11358519].

GO terms

Biological Process

GO:0045493 xylan catabolic process

Molecular Function

GO:0046559 alpha-glucuronidase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.