Domain

Peptide chain release factor (IPR005139)

Short name: PCRF

Domain relationships

None.

Description

This domain is found in peptide chain release factors. Peptide chain release factors are important for protein synthesis since they direct the termination of translation in response to the peptide chain termination codons UAG and UAA. These are structurally distinct but both contain the PCRF domain [PMID: 11779511].

GO terms

Biological Process

GO:0006415 translational termination

Molecular Function

GO:0016149 translation release factor activity, codon specific

Cellular Component

GO:0005737 cytoplasm

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
SMART