Vacuolar (H+)-ATPase G subunit (IPR005124)

Short name: V-ATPase_G

Family relationships



This family represents the eukaryotic vacuolar (H+)-ATPase (V-ATPase) G subunit. V-ATPases generate an acidic environment in several intracellular compartments. Correspondingly, they are found as membrane-attached proteins in several organelles. They are also found in the plasma membranes of some specialised cells. V-ATPases consist of peripheral (V1) and membrane integral (V0) heteromultimeric complexes. The G subunit is part of the V1 subunit, but is also thought to be strongly attached to the V0 complex. It may be involved in the coupling of ATP degradation to H+ translocation.

GO terms

Biological Process

GO:0015992 proton transport

Molecular Function

GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances

Cellular Component

GO:0016471 vacuolar proton-transporting V-type ATPase complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.