Family

EspA-like secreted protein (IPR005095)

Short name: EspA

Family relationships

None.

Description

EspA is the prototypical member of this family. EspA, together with EspB, EspD and Tir are exported by a type III secretion system. These proteins are essential for attaching and effacing lesion formation. EspA is a structural protein and a major component of a large, transiently expressed, filamentous surface organelle which forms a direct link between the bacterium and the host cell [PMID: 9545230, PMID: 10760148].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam