NADPH-dependent FMN reductase-like (IPR005025)

Short name: FMN_Rdtase-like

Overlapping homologous superfamilies

Domain relationships



This domain in found in several flavoproteins such as FMN-dependent NADPH-azoreductase, which catalyses the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines [PMID: 16752898], and NAD(P)H:quinone oxidoreductase, which reduces quinones to the hydroquinone state to prevent interaction of the semiquinone with O2 and production of superoxide [PMID: 9694845]. In Arabidopsis NADPH:quinone oxidoreductase is involved in detoxification pathways [PMID: 10606758]. NAD(P)H:quinone oxidoreductase prefers NADH over NADPH, while FMN-dependent NADPH-azoreductase requires NADPH, but not NADH, as an electron donor for its activity.

Other proteins with this domain include iron-sulfur flavoproteins [PMID: 11591665] and chromate reductase [PMID: 14766567].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.