Family

Pectinacetylesterase/NOTUM (IPR004963)

Short name: PAE/NOTUM

Family relationships

None.

Description

This family includes protein Notum from animals and pectinacetylesterase (PAE) from plants. Notum is a carboxylesterase that removes an essential palmitoleate moiety from Wnt proteins. Notum constitutes the first known extracellular protein deacylase [PMID: 25731175, PMID: 25771893]. PAEs catalyse the deacetylation of pectin, a major compound of primary cell walls [PMID: 12026180, PMID: 25115560].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016787 hydrolase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER