Family

Deoxyribonuclease II (IPR004947)

Short name: DNase_II

Family relationships

None.

Description

Deoxyribonuclease II (EC:3.1.22.1) hydrolyses DNA under acidic conditions with a preference for double-stranded DNA. It catalyses the endonucleolytic cleavage of DNA to 3'-phosphomononucleotide and 3'-phosphooligonucleotide end-products. The enzyme may play a role in apoptosis. This family also includes hypothetical proteins from Caenorhabditis elegans.

GO terms

Biological Process

GO:0006259 DNA metabolic process

Molecular Function

GO:0004531 deoxyribonuclease II activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER