Family

Gamma interferon inducible lysosomal thiol reductase GILT (IPR004911)

Short name: Interferon-induced_GILT

Family relationships

None.

Description

This family includes the two characterised human gamma-interferon-inducible lysosomal thiol reductase (GILT) sequences [PMID: 3136170, PMID: 10639150]. It also contains several other eukaryotic putative proteins with similarity to GILT [PMID: 11491538]. The aligned region contains three conserved cysteine residues. In addition, the two GILT sequences possess a C-X(2)-C motif that is shared by some of the other sequences in the family. This motif is thought to be associated with disulphide bond reduction.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
Pfam