Glycoside hydrolase family 63 (IPR004888)

Short name: Glycoside_hydrolase_63

Overlapping homologous superfamilies

Family relationships



O-Glycosyl hydrolases (EC:3.2.1.) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [PMID: 7624375, PMID: 8535779]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site.

This is a family of eukaryotic enzymes belonging to glycosyl hydrolase family 63 (GH63). They catalyse the specific cleavage of the non-reducing terminal glucose residue from Glc(3)Man(9)GlcNAc(2). Mannosyl oligosaccharide glucosidase EC: is the first enzyme in the N-linked oligosaccharide processing pathway.

GO terms

Biological Process

GO:0009311 oligosaccharide metabolic process

Molecular Function

GO:0004573 mannosyl-oligosaccharide glucosidase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.