Luc7-related (IPR004882)

Short name: Luc7-rel

Family relationships



This family consists of several Luc7 protein homologues that are restricted to eukaryotes. In budding yeast, Luc7 is an essential subunit of the yeast U1 snRNP, which forms the spliceosomal commitment complex with other proteins that targets pre-mRNA to the splicing pathway [PMID: 17726058, PMID: 11170747]. Its N-terminal zinc finger has been found to bind pre-mRNA [PMID: 17726058]. This entry also contains human and mouse Luc7 like (LUC7L) proteins [PMID: 10500099].

GO terms

Biological Process

GO:0006376 mRNA splice site selection

Molecular Function

GO:0003729 mRNA binding

Cellular Component

GO:0005685 U1 snRNP

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.