Domain

Cleavage/polyadenylation specificity factor, A subunit, C-terminal (IPR004871)

Short name: Cleavage/polyA-sp_fac_asu_C

Domain relationships

None.

Description

This family includes a region that lies towards the C terminus of the cleavage and polyadenylation specificity factor (CPSF) A (160 kDa) subunit. CPSF is involved in mRNA polyadenylation and binds the AAUAAA conserved sequence in pre-mRNA. CPSF has also been found to be necessary for splicing of single-intron pre-mRNAs [PMID: 11421366]. The function of the aligned region is unknown but may be involved in RNA/DNA binding.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003676 nucleic acid binding

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam