Calcineurin-like phosphoesterase domain, ApaH type (IPR004843)

Short name: Calcineurin-like_PHP_ApaH

Overlapping homologous superfamilies

Domain relationships


This domain is found in a diverse range of phosphoesterases [PMID: 9685491], including bis(5'-nucleosyl)-tetraphosphatase (apaH), nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases, as well as nucleases such as bacterial SbcD or archaeal/yeast Mre11. The most conserved regions in this domain centre around the metal chelating residues.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016787 hydrolase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.