Drug resistance transporter Bcr/CmlA subfamily (IPR004812)

Short name: Efflux_drug-R_Bcr/CmlA

Overlapping homologous superfamilies

Family relationships


The drug resistance transporter Bcr/CflA proteins are predicted to have 12 membrane-spanning regions. Members with known activity include Bcr (bicyclomycin resistance protein) in Escherichia coli [PMID: 8486276], Flor (chloramphenicol and florfenicol resistance) in Salmonella typhimurium [PMID: 15980376], and CmlA (chloramphenicol resistance) found on the Pseudomonas plasmid R1033 [PMID: 1648560].

GO terms

Biological Process

GO:0006855 drug transmembrane transport

Molecular Function

GO:0015238 drug transmembrane transporter activity

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.