Phosphotransferase system, cellobiose-type IIC component (IPR004796)

Short name: PTS_IIC_cello

Overlapping homologous superfamilies


Family relationships



The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system, catalyses the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. The phosphotransferase system consists of both the cellobiose-specific and the lactose-specific forms of the phosphotransferase system (PTS) IIC component. The IIC domain catalyses the transfer of a phosphoryl group from the IIB domain to the substrate. When the IIC component and IIB components are in the same polypeptide chain they are designated IIBC.

This family consists of the cellobiose-type IIC component of phosphotransferase systems (PTS), that includes transporters for cellobiose [PMID: 8407820], N,N'-diacetylchitobiose [PMID: 10913117], lichenan [PMID: 8990303] and glucomannan [PMID: 18177310].

GO terms

Biological Process

GO:0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system

Molecular Function

GO:0008982 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.