Polyol permease (IPR004748)

Short name: Polyol_permease

Overlapping homologous superfamilies

Family relationships


Proteins in this entry are mostly known or predicted polyol transporters. The best characterised of these proteins are DalT and RbtT from Klebsiella pneumoniae, which tranpsort D-arabinatol and ribotol respectively. Like other members of the Major Facilitator Superfamily (MFS), DalT and RbtT appear to be secondary transporters capable only of transporting solutes in response to chemiosmotic ion gradients [PMID: 9324246]. They contain a total of twelve predicted transmembrane helices; six in the N-terminal portion of the protein, and six in the C-terminal portion. Residues defining substrate specificity lie in the N-terminal region of these proteins.

GO terms

Biological Process

GO:0055085 transmembrane transport

Molecular Function

GO:0022857 transmembrane transporter activity

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.