Alkylhydroperoxidase AhpD (IPR004674)

Short name: AhpD

Family relationships



Alkyl hydroperoxide reductase AhpD catalyse the reduction of peroxides to their corresponding alcohols via oxidation of cysteine residues. In these alkylhydroperoxidases, the cysteines are located in a conserved -CXXC- motif located towards the C terminus. In Mycobacterium tuberculosis, two non-homologous alkylhydroperoxidases, AhpD and AhpC, are found in the same operon. This entry represents AhpD, which is a component of alkyl-hydroperoxide reductase participating in defense against ROS and ROS produced by host immune cells [PMID: 11799204].

GO terms

Biological Process

GO:0055114 oxidation-reduction process
GO:0006979 response to oxidative stress

Molecular Function

GO:0032843 hydroperoxide reductase activity
GO:0051920 peroxiredoxin activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.