2,4-diaminobutyrate 4-transaminase (IPR004637)

Short name: Dat

Overlapping homologous superfamilies

Family relationships


This family consists of L-diaminobutyric acid transaminases. This general designation covers both EC: (diaminobutyrate-2-oxoglutarate transaminase, which uses glutamate as the amino donor in DABA biosynthesis), and EC: (diaminobutyrate--pyruvate transaminase, which uses alanine as the amino donor). Most members with known function are EC:, and at least some annotations as EC: in current databases at time of model revision are incorrect. A distinct branch of this family contains examples of EC: nearly all of which are involved in ectoine biosynthesis. EC: has also been characterised as part of an alternative polyamine biosynthetic pathway in Vibrio cholerae. A related enzyme is 4-aminobutyrate aminotransferase (EC EC:, also called GABA transaminase. These enzymes all are pyridoxal phosphate-containing class III aminotransferase.

GO terms

Biological Process

GO:0009058 biosynthetic process

Molecular Function

GO:0008483 transaminase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.