Acetylornithine/Succinylornithine transaminase family (IPR004636)

Short name: AcOrn/SuccOrn_fam

Overlapping homologous superfamilies

Family relationships


This family of proteins, for which ornithine aminotransferases form an outgroup, consists mostly of proteins designated acetylornithine aminotransferase. However, the two very closely related members from Escherichia coli are assigned different enzymatic activities. One is acetylornithine aminotransferase (EC:, ArgD, an enzyme of arginine biosynthesis, while another is succinylornithine aminotransferase, an enzyme of the arginine succinyltransferase pathway, an ammonia-generating pathway of arginine catabolism [PMID: 9696779]. Members of this family may also act on ornithine, like ornithine aminotransferase (EC: [PMID: 2199330] and on succinyldiaminopimelate, like N-succinyldiaminopmelate-aminotransferase (EC:, DapC, an enzyme of lysine biosynthesis) [PMID: 10074354].

GO terms

Biological Process

GO:0006525 arginine metabolic process

Molecular Function

GO:0008483 transaminase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.