4-aminobutyrate aminotransferase, eukaryotic (IPR004631)

Short name: 4NH2But_aminotransferase_euk

Overlapping homologous superfamilies

Family relationships


4-aminobutyrate aminotransferase eukaryotic (EC: is a class III pyridoxal-phosphate-dependent aminotransferase. The enzyme catalyses the conversion of 4-aminobutanoate and 2-oxoglutarate into succinate semialdehyde and L-glutamate. The degree of sequence difference between this set and known bacterial examples is greater than the distance between either set the most similar enzyme with distinct function, and so the prokaryotic and eukaryotic sets have been placed into separate families. This family describes known eukaryotic examples of the enzyme. Alternate names include GABA transaminase, gamma-amino-N-butyrate transaminase, and beta-alanine--oxoglutarate aminotransferase.

GO terms

Biological Process

GO:0009448 gamma-aminobutyric acid metabolic process

Molecular Function

GO:0003867 4-aminobutyrate transaminase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.