Family

Transcription factor TFIIH subunit p52/Tfb2 (IPR004598)

Short name: TFIIH_p52/Tfb2

Family relationships

None.

Description

This entry represents the p52/Tfb2 subunit in the TFIIH complex, which is not only required for transcription but also plays a central role in DNA repair. The TFIIH multiprotein complex consists of a 7-subunit core (XPB, p62, p52, p44, p34, and TTDA) that is associated with a 3-subunit CDK-activating kinase module (MAT1, cyclin H and Cdk7) [PMID: 21592869, PMID: 22308316, PMID: 22572993].

GO terms

Biological Process

GO:0006289 nucleotide-excision repair

Molecular Function

GO:0004003 ATP-dependent DNA helicase activity

Cellular Component

GO:0000439 core TFIIH complex
GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER
TIGRFAMs