TFIIH C1-like domain (IPR004595)

Short name: TFIIH_C1-like_dom

Overlapping homologous superfamilies

Domain relationships



The carboxyl-terminal region of TFIIH is essential for transcription activity. This regions binds three zinc atoms through two independent domains. The first contains a C4 zinc finger motif, whereas the second is characterised by a CX(2)CX(2-4)FCADCD motif. The solution structure of the second C-terminal domain revealed homology with the regulatory domain of protein kinase C [PMID: 10882739].

GO terms

Biological Process

GO:0006281 DNA repair

Molecular Function

GO:0008270 zinc ion binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.