Family

tRNA modification GTPase MnmE (IPR004520)

Short name: GTPase_MnmE

Family relationships

None.

Description

MnmE, also called TrmE and previously designated ThdF (thiophene and furan oxidation protein), is a GTPase involved in tRNA modification to create 5-methylaminomethyl-2-thiouridine in the wobble position of some tRNAs [PMID: 10601028]. This protein and GidA form an alpha2/beta2 heterotetramer.

GO terms

Biological Process

GO:0006400 tRNA modification

Molecular Function

GO:0005525 GTP binding
GO:0003924 GTPase activity

Cellular Component

GO:0005622 intracellular

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
HAMAP
TIGRFAMs