DNA repair protein RadA (IPR004504)

Short name: DNA_repair_RadA

Overlapping homologous superfamilies

Family relationships



RadA/Sms is a highly conserved eubacterial protein that shares sequence similarity with both RecA strand transferase and lon protease. The RadA/Sms family are probable ATP-dependent proteases involved in both DNA repair and degradation of proteins, peptides, glycopeptides. They are classified in as non-peptidase homologues and unassigned peptidases in MEROPS peptidase family S16 (lon protease family, clan SJ).

RadA/Sms is involved in recombination and recombinational repair, most likely involving the stabilisation or processing of branched DNA molecules or blocked replication forks because of its genetic redundancy with RecG and RuvABC [PMID: 12446634].

GO terms

Biological Process

GO:0006281 DNA repair

Molecular Function

GO:0005524 ATP binding
GO:0003684 damaged DNA binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.