ParB/RepB/Spo0J partition protein (IPR004437)

Short name: ParB/RepB/Spo0J

Overlapping homologous superfamilies

Domain relationships



This domain is found in chromosomal and plasmid partition proteins related to ParB, including Spo0J, RepB, and SopB.

ParB is involved in chromosome partition [PMID: 9054507]. It localises to both poles of the predivisional cell following completion of DNA replication. ParB binds to DNA sequences adjacent to the origin of replication suggesting that this region is tethered to the poles of the cell at a specific time in the cell cycle.

Spo0J has been shown to bind a specific DNA sequence that, when introduced into a plasmid, can serve as partition site. Study of RepB, which has nicking-closing activity, suggests that it forms a transient protein-DNA covalent intermediate during the strand transfer reaction.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003677 DNA binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.