Family

GHMP kinase group 1 (IPR004422)

Short name: GHMP_kin

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This protein family contains several archaeal examples of beta-ribofuranosylaminobenzene 5-prime-phosphate synthase (beta-RFAP synthase), an enzyme involved in methanopterin biosynthesis [PMID: 12142414]. In some species, two members of this family are found. It is unclear whether both act as beta-RFAP synthase. This family is related to the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase). Members are found so far only in the Archaea and in Methylobacterium extorquens. They have an amino-terminal domain probably related to ATP binding.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
PIRSF
TIGRFAMs