Pathways & interactions
Literature: Signal-recognition particle receptor FtsY (IPR004390)
References used in this entry
The following publications were referred to in the abstract:
Role of SRP RNA in the GTPase cycles of Ffh and FtsY.
Peluso P, Shan SO, Nock S, Herschlag D, Walter P.
Biochemistry 40 15224-33 2001
PMID: 11735405 Related citations
Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation.
Shan SO, Chandrasekar S, Walter P.
J. Cell Biol. 178 611-20 2007
PMID: 17682051 Related citations
FtsY, the bacterial signal-recognition particle receptor, interacts functionally and physically with the SecYEG translocon.
Angelini S, Deitermann S, Koch HG.
EMBO Rep. 6 476-81 2005
PMID: 15815684 Related citations
The following publications were not referred to in the abstract, but provide useful additional information:
Substrate twinning activates the signal recognition particle and its receptor.
Egea PF, Shan SO, Napetschnig J, Savage DF, Walter P, Stroud RM.
Nature 427 215-21 2004
PMID: 14724630 Related citations
X-ray structure of the T. aquaticus FtsY:GDP complex suggests functional roles for the C-terminal helix of the SRP GTPases.
Gawronski-Salerno J, Coon JS 5th, Focia PJ, Freymann DM.
Proteins 66 984-95 2007
PMID: 17186523 Related citations
Structure of the GMPPNP-stabilized NG domain complex of the SRP GTPases Ffh and FtsY.
Gawronski-Salerno J, Freymann DM.
J. Struct. Biol. 158 122-8 2007
PMID: 17184999 Related citations
Heterodimeric GTPase core of the SRP targeting complex.
Focia PJ, Shepotinovskaya IV, Seidler JA, Freymann DM.
Science 303 373-7 2004
PMID: 14726591 Related citations
Structure of a GDP:AlF4 complex of the SRP GTPases Ffh and FtsY, and identification of a peripheral nucleotide interaction site.
Focia PJ, Gawronski-Salerno J, Coon JS 5th, Freymann DM.
J. Mol. Biol. 360 631-43 2006
PMID: 16780874 Related citations