Pathways & interactions
Literature: Signal-recognition particle receptor FtsY (IPR004390)
References used in this entry
The following publications were referred to in the abstract:
Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation.
Shan SO, Chandrasekar S, Walter P.
J. Cell Biol. 178 611-20 2007
PMID: 17682051 Related citations
FtsY, the bacterial signal-recognition particle receptor, interacts functionally and physically with the SecYEG translocon.
Angelini S, Deitermann S, Koch HG.
EMBO Rep. 6 476-81 2005
PMID: 15815684 Related citations
Role of SRP RNA in the GTPase cycles of Ffh and FtsY.
Peluso P, Shan SO, Nock S, Herschlag D, Walter P.
Biochemistry 40 15224-33 2001
PMID: 11735405 Related citations
The following publications were not referred to in the abstract, but provide useful additional information:
X-ray structure of the T. aquaticus FtsY:GDP complex suggests functional roles for the C-terminal helix of the SRP GTPases.
Gawronski-Salerno J, Coon JS 5th, Focia PJ, Freymann DM.
Proteins 66 984-95 2007
PMID: 17186523 Related citations
Structure of the GMPPNP-stabilized NG domain complex of the SRP GTPases Ffh and FtsY.
Gawronski-Salerno J, Freymann DM.
J. Struct. Biol. 158 122-8 2007
PMID: 17184999 Related citations
Structure of a GDP:AlF4 complex of the SRP GTPases Ffh and FtsY, and identification of a peripheral nucleotide interaction site.
Focia PJ, Gawronski-Salerno J, Coon JS 5th, Freymann DM.
J. Mol. Biol. 360 631-43 2006
PMID: 16780874 Related citations
Substrate twinning activates the signal recognition particle and its receptor.
Egea PF, Shan SO, Napetschnig J, Savage DF, Walter P, Stroud RM.
Nature 427 215-21 2004
PMID: 14724630 Related citations
Heterodimeric GTPase core of the SRP targeting complex.
Focia PJ, Shepotinovskaya IV, Seidler JA, Freymann DM.
Science 303 373-7 2004
PMID: 14726591 Related citations