Family

Peptide chain release factor 1 (IPR004373)

Short name: PrfA

Family relationships

None.

Description

This entry represents peptide chain release factor 1 (PrfA, RF-1), and excludes the related peptide chain release factor 2 (PrfB, RF-2). RF-1 helps recognise and terminate translation at UAA and UAG stop codons. Mitochondrial release factors are PrfA-like, but are not included in this entry. RF-1 does not have a translational frameshift.

GO terms

Biological Process

GO:0006415 translational termination

Molecular Function

GO:0016149 translation release factor activity, codon specific

Cellular Component

GO:0005737 cytoplasm

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs
HAMAP