Methylglyoxal synthase (IPR004363)

Short name: Methylgl_synth

Family relationships



Methylglyoxal synthase (MGS) [PMID: 10368300] catalyzes the conversion of dihydroxyacetone phosphate to methylglyoxal and phosphate: Glycerone phosphate = methylglyoxal + phosphate It provides bacteria with an alternative to triosephosphate isomerase for metabolizing dihydroxyacetone phosphate. MGS is a small protein of about 13 to 17 kDa. An aspartate residue is involved in the catalytic mechanism. Methylglyoxal synthase contains a domain shared by other enzymes. Other proteins containing this domain include purine biosynthesis protein PurH and carbamoyl phosphate synthetase.

GO terms

Biological Process

GO:0019242 methylglyoxal biosynthetic process

Molecular Function

GO:0008929 methylglyoxal synthase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.