Family

Vacuolar fusion protein Mon1 (IPR004353)

Short name: Mon1

Family relationships

None.

Description

Members of this family have been called SAND proteins [PMID: 15647795] although these proteins do not contain a SAND domain. In Saccharomyces cerevisiae, Mon1 is part of the Mon1-Ccz1 complex that acts as the guanine nucleotide exchange factor (GEF) of the yeast Rab7 GTPase Ypt7 [PMID: 24413168, PMID: 24623720]. The Mon1/Ccz1 complex is conserved in eukaryotic evolution and members of this family (previously known as DUF254) are distant homologues to domains of known structure that assemble into cargo vesicle adapter (AP) complexes [PMID: 10025966, PMID: 17075139].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PRINTS
Pfam
PANTHER