Family

Tubulin binding cofactor A (IPR004226)

Short name: CofA_tubulin-bd

Family relationships

None.

Description

The folding pathway of tubulins includes highly specific interactions with a series of cofactors (A, B, C, D and E) after they are released from the eukaryotic chaperonin CCT. Cofactors A and D capture and stabilise tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex, and interaction with cofactor C then causes the release of tubulin poypeptides in the native state. This family is the tubulin-specific chaperone A.

GO terms

Biological Process

GO:0007021 tubulin complex assembly

Molecular Function

GO:0051082 unfolded protein binding

Cellular Component

GO:0005874 microtubule

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER
ProDom
SUPERFAMILY