Domain

Prokaryotic glutathione synthetase, N-terminal (IPR004215)

Short name: GSHS_N

Overlapping homologous superfamilies

Domain relationships

None.

Description

Prokaryotic glutathione synthetase EC:6.3.2.3 (glutathione synthase) catalyses the conversion of gamma-L-glutamyl-L-cysteine and glycine to orthophosphate and glutathione in the presence of ATP. This is the second step in glutathione biosynthesis. The enzyme is inhibited by 7,8-dihydrofolate, methotrexate and trimethoprim. This domain is the N terminus of the enzyme.

GO terms

Biological Process

GO:0006750 glutathione biosynthetic process

Molecular Function

GO:0004363 glutathione synthase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam