Domain

Integrase, Tn916-type, N-terminal DNA binding (IPR004191)

Short name: Integrase_Tn916-type_DNA-bd_N

Domain relationships

None.

Description

The integrase family of site-specific recombinases catalyze a diverse array of DNA rearrangements in archaebacteria, eubacteria and yeast. The structure of the DNA binding domain of the the conjugative transposon Tn916 integrase protein was determined using NMR spectroscopy. The N-terminal domain was found to be structurally similar to the double stranded RNA binding domain (dsRBD). Experimental evidence suggests that the integrase protein interacts with DNA using residues located on the face of its three stranded beta-sheet [PMID: 9665166].

GO terms

Biological Process

GO:0015074 DNA integration

Molecular Function

GO:0003677 DNA binding
GO:0008907 integrase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam