Domain

Sec63 domain (IPR004179)

Short name: Sec63-dom

Domain relationships

None.

Description

This domain was named after the yeast Sec63 (or NPL1) (also known as the Brl domain) protein in which it was found. This protein is required for assembly of functional endoplasmic reticulum translocons [PMID: 16368690, PMID: 11023840]. Other yeast proteins containing this domain include pre-mRNA splicing helicase BRR2, HFM1 protein and putative helicases.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SMART
Pfam
SMART