WWE domain (IPR004170)

Short name: WWE-dom

Overlapping homologous superfamilies

Domain relationships


The WWE domain is named after three of its conserved residues and is predicted to mediate specific protein-protein interactions in ubiquitin and ADP ribose conjugation systems. This domain is found as a tandem repeat at the N-terminal of Deltex, a cytosolic effector of Notch signalling thought to bind the N-terminal of the Notch receptor [PMID: 16271883]. It is also found as an interaction module in protein ubiquination and ADP ribosylation proteins [PMID: 11343911].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE profiles