Active Site

Coenzyme A transferase active site (IPR004164)

Short name: CoA_transf_AS


Coenzyme A (CoA) transferases belong to an evolutionary conserved [PMID: 1624453, PMID: 9325289] family of enzymes catalyzing the reversible transfer of CoA from one carboxylic acid to another. They have been identified in many prokaryotes and in mammalian tissues. The bacterial enzymes are heterodimers of two subunits (A and B) of about 25 Kd each while eukaryotic SCOT consists of a single chain which is colinear with the two bacterial subunits. This signature corresponds to a region in the N terminus of the B subunit which contains a glutamate that is involved in the catalytic mechanism.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0008410 CoA-transferase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns