NAD-dependent DNA ligase, OB-fold (IPR004150)

Short name: NAD_DNA_ligase_OB

Overlapping homologous superfamilies

Domain relationships



DNA ligases catalyse the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor [PMID: 10698952]. This family is a small domain found after the adenylation domain DNA_ligase_N in NAD+-dependent ligases (IPR001679). OB-fold domains generally are involved in nucleic acid binding.

GO terms

Biological Process

GO:0006281 DNA repair
GO:0006260 DNA replication

Molecular Function

GO:0003911 DNA ligase (NAD+) activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.