Family

Dim1 family (IPR004123)

Short name: Dim1

Family relationships

None.

Description

This entry represents fission yeast Dim1 and its homologues, including Dib1 from budding yeasts, YLS8 from plants and TXNL4 from animals. Dim1 was originally identified as a mitosis protein [PMID: 9182666]. Later, it was found to interact with spliceosome component Prp6, which is involved in pre-mRNA splicing [PMID: 11054566]. Dim1 may act at the level of mRNA, which impacts the functioning of the APC/C, a critical complex in controlling mitotic progression [PMID: 15755920].

It's worth noting that although the Dim proteins exhibit a thioredoxin-like fold, they lack the disulfide bond required for the thioredoxin redox activity [PMID: 17558560].

GO terms

Biological Process

GO:0000398 mRNA splicing, via spliceosome

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005681 spliceosomal complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD
SMART
Pfam
PIRSF
PANTHER